Các dòng cột sắc ký Mix-mode của hãng SIELC Technologies

Cột sắc ký của hãng SIELC Technologies là dòng cột đặt thù, chuyên dùng trong các nghiên cứu khoa học, với những tính năng và chất lượng nổi trội. Được xem là hãng dẫn đầu trong lĩnh vực sản xuất cột mix mode, một dạng pha tính có những tính năng ưu việt trong phân tích sắc ký lỏng hiệu năng HPLC

SKU: SIELC HPLC Categories: ,

Cột sắc ký của hãng SIELC Technologies là dòng cột đặt thù, có tính năng đa cơ chế Mix-Mode, chuyên dùng trong các nghiên cứu khoa học, với những tính năng và chất lượng nổi trội. Được xem là hãng dẫn đầu trong lĩnh vực sản xuất cột mix mode, một dạng pha tính có những tính năng ưu việt trong phân tích sắc ký lỏng hiệu năng HPLC

Cột sắc ký của hãng SIELC Technologies đã và đang được các nhà khoa học trên khắp thế giới sử dụng trong các công trình nghiên cứu của mình.

Các dòng cột mix mode của hãng SIELC bao gồm:

Coresep™
SIELC Technologies has developed a new generation of unique stationary phases,  combining mixed-mode and core-shell approaches –  Coresep™.
Mixed-mode columns offer much higher capacity and retention than traditional reversed-phase columns. Since the surface area of core-shell particles is reduced, mixed-mode phases address potential loadability issues whilst maintaining the selectivity advantages of multiple interactions. Newly optimized ligand density and ionic / hydrophobic ratios further increases the capacity of mixed-mode core-shell columns.

Coresep 100

Coresep 100 is a reverse-phase analytical column with embedded acidic ion-pairing groups embedded on core-shell particles.

  • Improves retention of basic compounds by cation-exchange mechanism.
  • Separates acids by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Coresep 100 columns are available in all standard dimensions
Column IDs: 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 2.7 um
Pores: 90 A

Coresep S

Coresep S is a normal-phase analytical column with embedded acidic ion-pairing groups embedded on core-shell particles.

  • Most suitable for separation of common sugars and other neutral or very polar molecules.
  • Retains and separates amino acids with different buffers at low concentration.
  • Separates weak bases by ion-exchange mechanism.
  • Separate acids by ion-exclusion mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 2.0 to 7.0).

Coresep S columns are available in all standard dimensions
Column IDs: 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 2.7 um
Pores: 90 A

Coresep SB

Coresep SB is a reverse-phase analytical column with strong embedded basic ion-pairing groups embedded on core-shell particles.

  • Improves retention of acidic compounds by anion-exchange mechanism.
  • Separates bases by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 5).

Coresep SB columns are available in all standard dimensions
Column IDs: 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 2.7 um
Pores: 90 A

SHARC™
SHARC™ HPLC columns is the latest, innovative column from SIELC Technologies, the inventors of Primesep®.
SHARC™ columns are the first commercially available columns with separation based primarily on hydrogen bonding.

SHARC stands for  Specific Hydrogen-bond Adsorption ResolutionColumn.
Hydrogen bonding is an interaction (attraction) of bound hydrogen atom to the molecules with electronegative atoms such as oxygen, nitrogen, fluorine.
SHARC 1

SHARC columns are the first commercially available columns with separation based primarily on hydrogen bonding. SHARC stands for  Specific Hydrogen-bond Adsorption Resolution Chromatography. The SHARC 1 column is the first of the SHARC series columns.

SHARC1 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um, 3 um
Pores: 100 A

Primesep®
Primesep stationary phases offer unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. A wide range of HPLC columns with id’s from 0.5 mm to 22 mm is available. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service is available for customers. Ask about special custom LC-phases tailored for specific separations.

Cation-exchange Column Type About 50% of embedded acidic groups ionized at transition pH value Separates basic compounds
Primesep 500 pH = 5.0 strong bases, dibases, polybases
Primesep C pH = 3.5 strong bases, dibases
Primesep 200 pH = 2 strong bases, dibases
Primesep P pH = 1 weak, medium aromatic bases
Primesep 100 pH = 1 weak, medium bases, AA, metals
Primesep A Ionized in all working pH weak bases, AA, metals
Primesep A HPLC Columns

Primesep A is a reverse-phase analytical column with embedded strong acidic ion-pairing groups.

  • Improves retention of weak basic compounds by cation-exchange mechanism.
  • Separates acids by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep A columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep AB HPLC Columns

Primesep AB is a reverse-phase column with embedded acidic and basic ion-pairing groups.

  • Improves retention of strong acidic compounds and strong basic compounds by ion-exchange mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep AB columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep B2 HPLC Columns

Primesep B2 is a reverse-phase analytical column with embedded basic ion-pairing groups.

  • Improves retention of acidic compounds by anion-exchange mechanism.
  • Separates bases by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 7).

Primesep B2 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep C HPLC Columns

Primesep C is a reverse-phase analytical column with embedded complex-forming groups.

  • Improves retention of positively charged compounds by forming a host-guest complex.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep C columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep D HPLC Columns

Primesep D is a reverse-phase analytical column with embedded basic ion-pairing groups specifically design for direct plasma analysis.

  • Does not retain high-molecular weight plasma components.
  • Retains hydrophobic and acidic components.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 4).

Primesep D columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep N HPLC Columns

Primesep N is a normal-phase analytical column with embedded acidic groups.

  • Primesep N has embedded acidic groups with a pKa of about 5.
  • Improves retention of basic compounds by cation-exchange mechanism at pH > 5.
  • Separates polar compounds by HILIC mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep N columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 300 A, 100 A

Primesep SB HPLC Columns

Primesep SB is a reverse-phase analytical column with strong embedded basic ion-pairing groups.

  • Improves retention of acidic compounds by anion-exchange mechanism.
  • Separates bases by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 5).

Primesep SB columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep P HPLC Columns

Primesep P is a reverse-phase analytical column with embedded aromatic and acidic ion-pairing groups.

  • Improves retention of basic compounds by cation-exchange mechanism.
  • Separates aromatic compounds by difference in pi-pi interaction.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep P columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep 100 HPLC Columns

Primesep 100 is a reverse-phase analytical column with embedded acidic ion-pairing groups.

  • This is the most versatile column of the entire Primesep family for separation of a broad range of compounds.
  • Improves retention of basic compounds by cation-exchange mechanism.
  • Separates acids by ion-exclusion mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep 100 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep 200 HPLC Columns

Primesep 200 is a reverse-phase analytical column with embedded weak acidic ion-pairing groups.

  • Improves retention of strong basic compounds by cation-exchange mechanism.
  • Retains neutral compounds by reverse-phase mechanism.
  • Provides an additional interaction with polar molecules offering separation of isomers and structurally-related compounds.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep 200 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Primesep 500 HPLC Columns

Primesep 500 is a reverse-phase analytical column with embedded acidic ion-pairing groups.

  • Primesep 500 has an embedded carboxilic acid with a pKa of about 5.
  • Improves retention of basic compounds by cation-exchange mechanism at pH > 5.
  • Separates acids by ion-exclusion mechanism at a mobile phase pH > 5.
  • Retains basic compounds, as any RP column, at pH < 5
  • Retains neutral compounds by reverse-phase mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible.

Primesep 500 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Obelisc™
Two complimentary columns, Obelisc R and Obelisc N, based on Liquid Separation Cell ( LiSC ™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures.

Obelisc R HPLC Columns

Obelisc R is a reverse-phase analytical column and can be used in traditional, reversed-phase type applications.

  • Due to the presence of ionic groups and a long hydrophobic chain, Obelisc R offers additional retention and tuning that is not available with traditional reversed-phase columns.
  • Multiple separation modes (RP, NP, IE).
  • Mass spec, ELSD, preparative and low UV (<220 nm) compatible, low concentration buffers.

Obelisc R columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Obelisc N HPLC Columns

Obelisc N is a column which has very polar characteristics and works well for polar and charged analytes.

  • Obelisc N offers both positively and negatively charged groups to interact with positively or negatively charged analytes.
  • Multiple separation modes (NP, HILIC, IE).
  • In HILIC mode, Obelisc N offers different selectivity form other HILIC or bare silica columns.
  • Mass spec, ELSD, preparative and low UV (<220 nm) compatible, low concentration buffers.

Obelisc N columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 10 um, 5 um
Pores: 100 A

Promix™
Promix is an alternative chromatography technology for efficient resolution of peptides and proteins. The technology is based on a combination of two interactions – hydrophobic and ionic. This approach is possible due to a new type of separation media: a chemical combination of hydrophobic and ionic functional groups on a ligand bonded to a silica support. With this phase, unparalleled selectivity and peak capacity can be achieved. Independent adjustment of the amount of buffer and organic modifier creates aninfinite number of separation conditions that are suitable for many types of biomolecules.

Promix AP HPLC Columns

Promix AP is a stationary phase for small and medium size peptides under 3 kDa with PI value below 7.0.

  • Reverse phase and ion-exchange mechanism of interaction.
  • Use acidic mobile phase pH from 2 to 5.5.
  • Use ion strength at least 20 mM.
  • 100Å and 300Å pore sizes are available.

Promix AP columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 5 um
Pores: 300 A, 100 A

Promix MP HPLC Columns

Promix MP is a stationary phase for medium size proteins and peptides from 1 to 10 kDa.

  • Broad pI value.
  • Reverse phase and ion-exclusion mechanism of interaction.
  • Use acidic mobile phase pH from 2 to 5.5.
  • Use ion strength at least 1 mM.
  • 300Å and 800Å pore sizes are available.

Promix MP columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 5 um
Pores: 800 A, 300 A

Promix SP HPLC Columns

Promix SP is a stationary phase for small peptides under 1 kDa with PI value below 6.0.

  • Reverse phase and ion-exchange mechanism of interaction.
  • Use acidic mobile phase pH from 2 to 5.5.
  • Use ion strength at least 20 mM.
  • 100Å pore size is available.

Promix SP columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm, 1 mm, 0.5 mm, 0.25 mm
Column Lengths: 250 mm, 150 mm, 100 mm, 50 mm, 25 mm, 10 mm
Particles: 5 um
Pores: 100 A

Legacy™
SIELC has developed the Legacy column, which can be used in many USP Validated methods. SIELC is developing L1, L3, L7, L8, L10, L11, L14, L16, L26, L28, and L44 columns.

gmLab Technologies nhập khẩu và phân phối các sản phẩm chuyên dùng này tại Việt Nam, sản phẩm này có tính cạnh tranh mạnh về mặt chất lượng, tính ổn định, và tính mới chuyên dùng trong phát triển phân tích hoặc nghiên cứu khoa học chuyên ngành. Để có thêm thông tin cụ thể về các loại cột sắc ký lỏng này, hoặc bạn đang cần tìm kiếm part number cho dòng cột mà mình muốn mua, vui lòng liên hệ với chúng tôi qua mail: sale@gimitec.com/gml

HPLC Applications By Publication Date
2013/12/05 Analysis of Lactic Acid on Primesep D Column
Analysis of Methylene Blue Purity in Reversed-Phase Cation-Exchange and Reversed-Phase Cation-Exclusion Modes
Fast Separation of Cannabinoids on Mixed-Mode Core-Shell HPLC Column
HPLC Analysis of Histones
HPLC Separation of Adenosine Mono-, Di- and Triphosphate in Reversed-Phase Mixed-Mode with LC/MS Compatible Conditions
Separation of Guanosine Diphosphate Mannose and Guanosine Diphosphate Fucose in Mixed-Mode Chromatography
Separation of Herbicides Paraquat, Diquat and Glyphosate in One Run with LC/MS Compatible Conditions
2013/07/10 Analysis of Hydrophobic Drugs on Core-Shell Mixed-Mode HPLC Column
Fast Dye Separation on SHARC 1 Column
Fast HPLC Separation of Homovanillic and Vanilmandelic Acids on Core-Shell
Fast HPLC Separation of Hydrophilic Acids on Core-Shell Mixed-Mode Column
HPLC Analysis of Ascorbic Acid on Core-Shell mixed-Mode Column
HPLC Analysis of Dextromethorphan and Bromide Counter-Ion on Coresep SB Column
HPLC Dye Separation on SHARC1 Column
HPLC Separation of Aminopyridines in Non-Aqueous Mobile Phase
HPLC Separation of Isomers of Nitrophthalic Acid on Core-Shell Mixed-Mode Column
HPLC Separation of Isomers of Phthalic Acids
Methanol and Ethanol Concentration Effect on Alizarin Retention on SHARC1 Column
Paraquat Diquat Separation in Non-aqueous Mobile Phase
2013/07/03 Analysis of Codeine and Related Impurities in Drug Composition
Analysis of Dextromethorphan-Based Composition
Analysis of Dextromethorphan-Based Drug composition. Effect on buffer pH
Analysis of Folic Acid and Related Impurities
HPLC Analysis of Xylitol on Primesep S Column
HPLC Analysis on Xylose and Xylitol on Primesep S Column
HPLC UV Analysis of Copper Ions in Salt Mixture
Method for Analysis of Glyphosate in Apple Juice, Cranberry Juice, Mango Juice and Green Tea
Retention of Azide Ion on Obelisc N Column
Retention of Sialic Acid on Primesep D Column
Retention of Taurine on Obelisc N Column
Retention of Taurine on SHARC Column
Separation of Compounds in TCA Cycle on Primesep D Column
Separation of Malonic Acids on Coresep SB Column
Separation of Paraquat, Diguat, and Glyphosate on Obelisc R Column
2013/07/02 Analysis of Codeine-Based Drug Composition. Effect of Buffer Concentration and Buffer pH
Analysis of Compounds of TCA Cycle on SHARC 1 Column
Efficiency of Separation for Amino Acids in HILIC/Cation-Exchange Mode
Efficiency of Separation for Dopamine and Epinephrine in HILIC/Cation-Exchange Mode
Efficiency of Separation for Uracil and Uridine in HILIC Mode
Fast and Effective Separation of Model Compounds on Core-Shell Column in Reversed-Phase and Mixed-Mode. Benefits of Mixed-Mode for Complex Mixtures
Fast and Effective Separation of Neurotransmitters on Core-Shell Column in Reversed-Phase Cation-Exchange Mode
Fast HPLC Separation of Underivatized Amino Acids on Core-Shell Column in Reversed-Phase and Mixed-Mode
HPLC Separation of Amino Acids on Core-Shell Column in Reversed-Phase and Mixed-Mode. BLIS Separation of Amino Acids
HPLC Separation of Atenolol on Legacy L1 Column
HPLC Separation of Epinephrine on Legacy L1 Column
HPLC Separation of Lecithin and Soy lecithin on Primesep N Column
HPLC Separation of Niacin on L1 Column
HPLC Separation of Norepinephrine on Legacy L1 Column
HPLC Separation of Praziquantel on Legacy L1 Column
Selectivity Difference for Polar Compounds on Core-Shell Column in Reversed-Phase and Mixed-Mode
Separation of Amino Aids in HILIC/Cation-Exchange Mode
Separation of Bisphenol A and Bisphenol A Glucoronide
Separation of Dopamine and Epinephrin in HILIC/Cation-Exchange Mode
Separation of Phthalic Acids and Related Impurities
Separation of Toluidine Isomers in HILIC/Cation-Exchange Mode
The Separation of Sodium, Dioctylsulfosuccinic Acid, and Sulfosuccinic Acid
Ultra-Fast HPLC Separation of Nucleobases on Core-Shell Column in Reversed-Phase Mixed-Mode
2012/07/23 HPLC Separation of Nucleosides and Deoxynucleosides
USP Methods for the Analysis of Procainamide
USP Methods for the Separation of Propranolol and Procainamide Using the Legacy L1 Column
2012/07/13 USP Methods for the Analysis of Norepinephrine using the Legacy L1 Column
2012/07/11 HPLC Separation of Inosine and Deoxyinosine
HPLC Separation of Succinylcholine and Choline Using a Primesep 200 Column
HPLC Separation of the Nonionic Surfacant Triton-X-100
2012/07/10 HPLC Analysis of Azide Ion on Obelisc N Column
HPLC Analysis of Bendamustine and Related Impurities
HPLC Analysis of Calcium Ions in Maple Syrup
HPLC Analysis of Inosine on Primesep 100 Column
HPLC Analysis of Piperazine on Primesep Columns
HPLC Analysis of Sulfosuccinic Acid on a Primesep S Column
HPLC Separation of 1-Methylhistidine and 3-Methylhistidine on Primesep 200
HPLC Separation of DOPAC, Homovanillic Acid and Dopamine on the Primesep 100 Column
HPLC Separation of DOPAC, Homovanillic Acid in Dopamine on the Primesep 200 Column
HPLC Separation of Lysine and Arginine from Other Amino Acids
HPLC Separation of Maleic Acid and Pentaerythritol
HPLC Separation of Organic Acids
HPLC Separation of Phosphorous and Phosphoric Acids
HPLC Separation of Sodium, Dioctyl Sulfosuccinic Acid, and Sulfosuccinic Acid
2012/07/03 HPLC Separation of Aminopyridines Isomers in Hydrogen-Bonding mode on a SHARC 1 HPLC Column
2012/06/21 USP Analysis of Albuterol Using a Legacy L1 Column
USP Analysis of Dopamine Using a Legacy L1 column
USP Method for the Analysis of Amoxicillin using the Legacy L1 Column
USP Methods for Chloramphenicol using a Legacy L1 Column
USP Methods for Nitrofurantoin for the Legacy L1 Column
USP Methods for the Analysis Ketoprofen using the Legacy L1 Column
USP Methods for the Analysis of Aminocaproic Acid using the Legacy L1 Column
USP Methods for the Analysis of Amitriptyline using a Legacy L1 Column
USP Methods for the Analysis of an Analgesic Mixture Using the Legacy L1 Column
USP Methods for the Analysis of Aspirin Using Legacy L1 Column
USP Methods for the Analysis of Atenolol using the Legacy L1 Column
USP Methods for the Analysis of Caffeine using the Legacy L1 Column
USP Methods for the Analysis of Epinephrine Using the Legacy L1 Column
USP Methods for the Analysis of Guaifenesin Using a Legacy L1 Column
USP Methods for the Analysis of Hydrocortisone on a Legacy L1 Column
USP Methods for the Analysis of Ibuprofen using a Legacy L1 Column
USP Methods for the Analysis of Ibuprofen Using Legacy L1 Column
USP Methods for the Analysis of Naproxen Using Legacy L1 Column
USP Methods for the Analysis of Niacin with the Legacy L1 Column
USP Methods for the Analysis of Praziquantel using the Legacy L1 Column
USP Methods for the Analysis of Prednisolone with the Legacy L1 Column
USP Methods for the Analysis of Pyridoxine for the Legacy L1 Column
2012/06/18 HPLC Separation of Adenosine and Adenine Using the Hydrogen Bonding Method
HPLC Separation of Cytidine and Cytosine Using the Hydrogen Bonding Method
HPLC separation of Dihydroxybenzoic acid in Hydrogen-Bonding mode on SHARC 1 HPLC column
HPLC Separation of Homovanillic Acid, Dopamine, and DOPAC using Hydrogen Bonding
HPLC Separation of Phthalic Acids using Hydrogen Bonding
2012/06/15 HPLC Separation of Caffeine, 3- Methylxanthine, 1- Methylxanthine, Xanthine
HPLC Separation of Pseudoephedrine, Norephedrine, Phenylephrine, and Norphenylephrine Using Hydrogen Bonding Mode
HPLC Separation of Pyrilamine, Trimipramine, Pindolol Using Hydrogen Bonding Mode
HPLC Separation of Thymidine, Uridine, Adenosine, Guanosine, and Cytidine Using the Hydrogen Bonding Method
2012/02/15 Analysis of m-Xylylenediamine (MXDA)
2011/11/25 HPLC Separation of Neurotransmitters
2011/07/14 HPLC Separation of Amino Acids in HILIC and Cation-Exchange Modes
HPLC Separation of Aminobiphenyl Isomers in Cation-Exchange Mode
HPLC Separation of Dopamine and Epinephrine in HILIC and Cation-Exchange Modes
HPLC Separation of Organic Acids in HILIC and Anion-Exclusion Mode on Primesep S2 Column
HPLC Separation of Sugars on Primesep S2 Column
HPLC Separation of Toluidine Isomers in Cation-Exchange Mode
HPLC Separation of Uracil and Uridine in HILIC Mode on Primesep S2 Column
2011/07/08 Effect of pH on Separation of Glyphosate and Ethylphosphonic Acid
HPLC Analysis of Metformin
HPLC Separation of 2-HEP and 2-HPP in the Presence of Methylcobalamin and Amino Acids
HPLC Separation of Amino Acids in Zero Organic Mode on Primesep 200 column
HPLC Separation of Aromatic Boronic Acids
HPLC Separation of Barium Cation in the Presence of Citric Acid, Sucrose and Tween 80
HPLC Separation of Benzalkonium Chloride BCT 8358 on Primesep D column
HPLC Separation of Catecholamines on Primesep 100 Column with Phosphate Buffers
HPLC Separation of Cetylpyridinium Chloride and Triethylene Glycol
HPLC Separation of Cyclodextrin Sulfobutyl Ether and Hydrophobic Compound
HPLC Separation of Glutamic Acid and GABA
HPLC Separation of Octopamine and Synephrine on Primesep 200 column
Separation of Maleic and Succinic Acid on Primesep B2 column
Separation of Mepiquat on Obelisc R Column
Separation of Small Lysine-based Peptide Oligomers
Simultaneous Analysis of Glucose, Sodium, Potassium and Calcium Ions
Simultaneous Separation of Melamine and Cyanuric Acid
2011/07/07 Separation of Sodium, Tetramethylammonium and Tetrabutylammonium on Primesep 200 Column
2011/06/05 HPLC Separation of Epinephrine and Epinephrine Sulfonate
2011/06/04 HPLC Analysis of Fatty Acids with MS Compatible Conditions
HPLC Separation of Heparines and Pentosan
HPLC Separation of NyQuil Active Ingredients
2011/05/06 HPLC Separation of Human and Synthetic Insulins on Promix Column
2011/03/27 HPLC Separation of 8 Generic Compounds on Primesep Columns
HPLC Separation of Hydrocortisone and Hydrocortisone’s Degradation Products
HPLC Separation of Isomers of Aminobenzoic Acid
HPLC Separation of Pyridinecarboxylic Acids
HPLC Separation of TRIS
2010/12/06 HPLC Separation of Benzenesulfonic and p-Toluenesulfonic Acids
2010/11/21 HPLC Retention of Aminopyrazole
HPLC Retention of EDTA in Sulfated CD
HPLC Retention of N-Cyclohexylsulfamic Acid
HPLC Separation of Acidic, Basic, and Neutral Compounds
HPLC Separation of Alkyl Sulfonic Acids
HPLC Separation of Ascorbic and Dehydroascorbic Acids
HPLC Separation of Codeine, Oxycodone, and Hydrocodone
HPLC Separation of Cytidines
HPLC Separation of Dihydroxybenzoic Acid
HPLC Separation of Drugs
HPLC Separation of Dyes
HPLC Separation of Inorganic Anions
HPLC Separation of Isomers of Amino Salicylic Acid
HPLC Separation of Morpholino Sulfates
HPLC Separation of Phenylephrine with Tannic Acid Formulation
HPLC Separation of Serine, a-Methylserine, GABA, and Methionine Mixture
HPLC Separation of Sodium, Chloride, Bromide, and Iodine
HPLC Separation of Tetracyclines
HPLC Separation of Uridine and Uracil
2010/11/12 HPLC Separation of Succinic and Methylmalonic Acids
2010/10/14 HPLC Analysis of ACE Serum Active Ingredients
HPLC Analysis of Active Drug and Amino Acids in a Formulation
HPLC Analysis of Citrulline and Arginine on Primesep Columns
HPLC Analysis of Hop Extract (Beer Brewing)
HPLC Analysis of L-Cysteine-S-Sulfate on Primesep SB Column
HPLC Analysis of Polylysine on Primesep AP Column
HPLC Analysis of Pseudoephedrine and Citric Acid on Primesep Column
HPLC Analysis of Sulfate and Phosphate Ions on Primesep Columns
HPLC Separation of Acetic acid and Acetic Hydrazide
HPLC Separation of Caffeine and Phenylephrine
HPLC Separation of Methylphosphonic Acid and Related Products
HPLC Separation of Saccharin and Sorbitol
HPLC Separation of Sugar Phosphates
2010/10/12 HPLC Separation of Polar Drugs with MS-compatible Method
2010/10/11 HPLC Separation of Quinine and Quinidine
2010/10/06 HPLC Separation of Mixture of Paraquat and Diquat
2010/10/04 HPLC Analysis of Active Drug in a Formulation
HPLC Separation of Acidic Drugs and Counter-Ions on Obelisc R Column
HPLC Separation of Aspartic Acid and Asparagine on Obelisc R Column
HPLC Separation of Methyl Paraben, Benzonitrile, Propyl Paraben, and Toluene on Mixed-Mode and Reverse Phase Columns
HPLC Separation of Prednisolone, Atrolactic Acid, and Ibuprofen on Mixed-Mode Column
HPLC Separation of Tylosin and Albendazole
2010/09/24 HPLC Application for Determination of Melamine in Baby Formula
2010/08/22 HILIC Retention of Polar Compounds on Primesep S
HPLC Analysis of Drugs in Saliva
Separation of Drugs in Mixed-Mode HPLC
Separation of Vitamins in Mixed-Mode HPLC
2010/08/07 HPLC Separation of Histamine and Phenethylamine
2010/07/16 HPLC Derivatization and Quantitative Analysis of Glycerol
2010/07/15 HPLC Separation of Lactic Acid and Its Oligomers
2010/07/08 Acid Effect on Retention of Acidic Analytes
2010/06/24 HPLC Separation of Cidofovirs Mixture
2010/06/04 HPLC Analysis of Polyethylenimine in Plasma
2010/05/06 HPLC Analysis of Apple Extract using Mixed-Mode Chromatography
HPLC Analysis of Polar Basic and Acetic Compounds on Primesep AB Column
HPLC Analysis of Valproic Acid using Mixed-Mode Chromatography
2010/05/05 Separation of Sodium, Potassium, Lithium, and Ammonium in Mixed-Mode HPLC
Separation Study of Fentin Acetate in Mixed-Mode HPLC
Separation Study of Zemuron Active Ingredient in Mixed-Mode HPLC
2010/04/27 Effect of Buffer and Chemistry of Column Stationary Phase on Resolution of Neutral Compounds
Effect of Buffer Concentration on Resolution of Neutral Compounds (Prednisolone and D-Glucose Pentaacetate)
HILIC Separation of Hydroxypiperidine and Impurities
2010/04/10 HPLC Separation of Acidic, Basic and Zwitterionic Compounds on Special Columns for Retention of Polar Compounds
2010/03/03 Comparison of Obelisc N, SeQuant® HILIC, and Bare Silica
Comparison of Obelisc R to C18 columns for the Separation of Aminopyridine Isomers
Comparison of the Separation of Polar Drugs on Obelisc R and Zorbax SB-AQ
Effect of both pH and Organic Content on a Separation of Sugars, Amino Acids, and Carboxylic Acids
Effect of mobile phase composition on retention of 3 compounds on Obelisc R
HILIC Separation of Sugars on Obelisc N
HPLC Separation of alpha-Aminobutyric, beta-Aminobutyric, and gamma-Aminobutyric acids on Obelisc N
HPLC Separation of Glyphosate Reaction Intermediates and Impurities
HPLC Separation of Potassium, Perchlorate, Methanesulfonic, Chloride, Bromide, and Nitrate Ions on Obelisc N
HPLC Separation Paraquat and Diquat on Obelisc R
2010/01/13 Effect of pH on Retention of Basic Compounds on Primesep C Columns
HPLC Separation of Glyphosate Production Intermediates
HPLC Separation of Polar Compounds
2009/07/16 HPLC Analysis of Polysorbate in Mixture with Amino Acids and Sugar
2009/07/16 HILIC Retention of 1,5-Naphthalenedisulfonic Acid on Obelisc N Mixed-Mode HILIC Columns
HILIC Separation of Common Preservatives – Citric Acid, Ascorbic Acid and EDTA
HPLC Analysis of 5-Fluorouracil on Primesep Columns with LC/MS Compatible Mobile Phase
HPLC Analysis of Alginic Acid in Heartburn Tablets
HPLC Analysis of Basic Drugs and Acidic Counter-Ions by Mixed-Mode Chromatography
HPLC Analysis of Motrin Cough & Cold Composition
HPLC Method for Determination of Lysine in Ibuprofen Lysine Composition
HPLC Method for Separation of Urea and Hydrogen Peroxide
HPLC Retention of Copper Ion on Primesep 100 Mixed-Mode Cation-Exchange Columns
HPLC Retention of Diazacon on Primesep B2 Mixed-mode Anion-Exchange Column
HPLC Retention of Sulfamic Acid on Primesep SB Mixed-Mode Column
HPLC Separation of Amino Acids in Supplements Composition in Mixed-Mode
HPLC Separation of Citric Acid and Phosphate Ions in HILIC Chromatography
HPLC Separation of Components of Excedrin
HPLC Separation of DMSO and Glycine by Mixed-Mode Chromatography
HPLC Separation of Epinephrine and Related Impurities
HPLC Separation of Sulfamic and Sulfuric Acid on Primesep N HILIC Column
Simultaneous Determination of Sodium and Sulfate Ions on Obelisc N Mixed-mode HILIC Column
2008/09/14 HPLC Analysis of Components of Ionic Liquids by Mixed-Mode Chromatography
2008/09/02 HPLC Separation of 5-Methyltetrahydrofolic Acid and Degradation Products
2008/08/22 HPLC Separation of Drugs in Advil Allergy and Sinus
HPLC Separation of Drugs in Tylenol Cold and Cough Remedies
Retention of Amikacin on Obelisc R Column
2008/08/22 Effect of Buffer on HPLC Separation of Buffers
HILIC Retention of Uridine and Uracil on Sielc’s HILIC Columns
HILIC Separation of Aromatic Acids
HILIC Separation of Carboxylic Acids
HILIC Separation of Carboxymethylcysteine and Betaine
HILIC Separation of Epinephrine and Epinephrine Sulfonate
HILIC Separation of Polyethylene Glycol
HILIC Separation of Ritonavir and Ribavirin
HILIC Separation of Surfactant Triton X-100
HILIC Separation of Vitamins Group B
HPLC Retention of Fentin Acetate
HPLC Retention of Glucosamine
HPLC Retention of Obidoxime
HPLC Retention of Polysorbate on Primesep D Column
HPLC Retention of Sulfuric Acid on Obelisc N Column
HPLC Separation of Antibiotics in Fish Production
HPLC Separation of Bendazoles on Primesep P Column
HPLC Separation of Benzenesulfonamide and Sulfanilamide
HPLC Separation of Dequalinium and Benzonitrile on Different Columns
HPLC Separation of GABA and GLU
HPLC Separation of m-Cresol Purple and Related Impurities
HPLC Separation of Neurotransmitters
HPLC Separation of Neurotransmitters and Related Drugs
HPLC Separation of Nitroprusside and its Metabolites
HPLC Separation of Surfynol 420
HPLC Separation of Vitamin C, Vitamin Group B, and Related Impurities
Retention of N-Nitrosarcosine on Obelisc N Column
Retention of TFA on Atlantis and Obelisc N
Separation of Alginic Acid and Related Products
Separation of Serotonin, Dopamine, and Related Compounds
2008/07/05 HPLC Analysis of TFA
2007/12/06 HPLC Separation of Impurities of Aminosugar
2007/12/06 HPLC Application for Analysis of EDTA
HPLC Application for Analysis of Sodium Succinate on Primesep 100
HPLC Application for Retention of Guanidine by Mixed-Mode Chromatography
HPLC Application for Separation of Nucleotide Bases
HPLC Application for Simultaneous Separation of Amino Acids, Hydrophilic Acidic and Hydrophobic Neutral Compounds
HPLC Separation of 3-Nitrophthalic and 4-Nitrophthalic Acids on Primesep D HPLC Column
HPLC Separation of Amino Acids
HPLC Separation of Aromatic Sulfonamides and Hydrozine
HPLC Separation of Common Antibiotics in Fish Farming
HPLC Separation of Isopropylamine and Glyphosate
HPLC Separation of Nucleobases (2)
HPLC Separation of Organic Acids in HILIC Mode on Primesep N Column
HPLC Separation of Sulfate and Phosphate Ions on Mixed-Mode HPLC
HPLC Separation of Taurine
Mixed-Mode HPLC Separation of Tertiary Amines on Primesep 200 Column
Mixed-Mode Retention and Separation of Ammonia, Primary and Secondary Amines on Primesep A Column
MS-compatible HPLC Separation of Diphosphate Anion
2007/10/04 HPLC Separation of Amino Acids on Obelisc R Column
HPLC Separation of Aromatic Compounds (PAH) on Mixed-Mode and Reverse Phase Columns
HPLC Separation of Explosives
HPLC Separation of Guanidine and Benzoic Acids on Primesep 100 Column
HPLC Separation of Phenylalanine, Glucosamine, and Tryptophan on Mixed-Mode Column
2007/03/03 HPLC Separation of Amino Acids, Bases, Acids, and Neutrals on Obelisc R
HPLC Separation of Nucleic Bases at pH 4 and 5 on Obelisc N
HPLC Separation of Polar and Hydrophobic Drugs on Obelisc R and N
2006/12/05 HPLC Separation of Ethanolamines
2006/11/21 HPLC Retention of Trimipramine
HPLC Separation of Aromatic Diamine Disulfate
HPLC Separation of Cetylpyridinium
HPLC Separation of Citrulline and Arginine
HPLC Separation of Organics Acids
HPLC Separation of Surfactants
HPLC Separation of Vanilmandelic, Hydroxyindoleacetic, and Homovanillic Acids
HPLC Separation of Vitamin C and Vitamin B2
2006/11/06 HPLC Separation of Coffee
2006/10/14 Complex Mixture of Acids, Bases, Amino Acids, and Neutral Compounds
2006/10/04 Separation of Simple Amines and Ammonia
2006/09/18 Amino Acids Analysis in Acid Gradient Condition
2006/08/12 Reverse Elution Order in Separation of Alkali Cation
2006/06/06 HPLC Retention of Ethylglucuronide
HPLC Separation of Alendronic, Ibandronic, Etidronic Acids
2006/06/05 HPLC Separation of Guaifenesin and Terbutaline
HPLC Separation of Parabens and Benzoic Acid
2006/03/27 HPLC Separation of Glucosamine from Chondroitin Sulfate
2006/03/03 HPLC Separation of Acetaminophen, Phenylephrine, and Diphenhydramine
HPLC Separation of Compounds of Catecholamine Pathway
2005/12/31 HPLC Separation of Toluidine Isomers
2005/11/20 Effect of Concentration of Organic Modifier on Retention of Cation and Anions
2005/11/15 Neutral, Base, and Acid on Primesep B Column
Simultaneous Separation of Cations and Anions
2005/11/14 Neutral, Base, and Acid on Primesep 100 Column
Neutral, Base, and Acid on Primesep 200 Column
Neutral, Base, and Acid on Primesep A Column
Nickel Contamination in Hydrogenation Products
2005/10/15 Complex of Cations on Primesep C is Effected by Organic Modifier
Separation of Steroids in Reverse and Normal Mode on Primesep 100 Column
Separation of Zn and Mn on Primesep 100 Column
2005/10/12 Control of Cation Exchange Properties by pH of Primesep C Column
Mixed-Mode Separation of Dihydroxybenzoic Acids
2005/10/11 Separation of Diacid Hydrophobic and Ion Exchange Modes
Zn and Na Quantitation in Drug Substances
2005/10/04 Separation of Diacid Hydrophobic and Ion Exclusion Modes
Separation of Guanidine
Separation of Metal Ions on Primesep 100 Column
Separation of Sulphonium Ions in Polar Organic Mode
2005/09/25 Separation of Simple Tertiary Amines
2005/09/18 Peak Symmetry Study with Amitryptiline
2005/08/06 Reverse Mode vs Normal Mode: Separation of Aromatic Compounds
2005/05/06 HPLC Analysis of Cheese Extract using Mixed-Mode Chromatography
HPLC Analysis of Gemfibrozil and Ibuprofen Using Mixed-Mode Chromatography
2005/05/05 Retention Characteristics of Betaine in Mixed-Mode HPLC
Separation and Retention of Dextromethorphan Bromide in Mixed-Mode HPLC: Buffer Concentration Effect
Separation and Retention of Vitamins in Mixed-Mode HPLC
Separation of Aromatic Carboxylic Acids by Mixed-Mode HPLC
Separation of Pyrazines by Mixed-Mode HPLC
Separation of Sulfonamides and Phenylhydrazine by Mixed-Mode HPLC
2005/04/27 Retention of Aminolevulinic Acid in Mixed-Mode System
2005/04/10 HPLC Separation of Amino Acids in Supplements Capsules
HPLC Separation of Aminobiphenyls
2005/01/30 Bufferless Ion Separation (BLIS™) Chromatography of Amino Acids (2)
2005/01/30 Bufferless Ion Separation (BLIS™) Chromatography of Aspartame: Organic Modifier Effect
2005/01/13 Bufferless Ion Separation (BLIS™) Chromatography of Amino Acids (1)
HPLC Separation of Active Compounds in Drug Formulation
HPLC Separation of Carboxylic Acids
HPLC Separation of Chloride and Nitrate Ions
HPLC Separation of Creatine, Creatinine and Histidine
HPLC Separation of Creatine, Creatinine and Histidine with MS Conditions
2004/06/29 HPLC Separation of Cotinine Metabolites
2004/06/10 Improved Peak Shape of a Basic Compound on Primesep B2 Column
2004/05/13 HPLC Separation of Two Vitamins: Different Polarity – Isocratic Methods
2004/05/06 HPLC Separation of Acetylcholines
HPLC Separation of Isomers of Aminobutyric Acids
2004/04/13 HPLC Separation of Gentamicins
HPLC Separation of Polyamines
2004/04/05 TFA Concentration Effect on Retention of Tricine
2004/04/03 HPLC Separation of Vitamin B
2004/03/27 HPLC Separation of Albuterol and Amoxicillin
HPLC Separation of Chlorate and Bromate Ions
HPLC Separation of Vitamin E and Vitamin E Acetate
Primesep C Column Retention Control
2004/03/02 Separation of NyQuil Active Ingredients on Primesep C
2004/02/11 Cetylpyridinium Methods with Good Efficiency and Peak Symmetry
2004/01/17 HPLC Analysis of the Catecholamine Pathway
Separation of Epinephrine Norepinephrine
2004/01/16 Separation of Quaternary Amines by Reverse-Phase Mechanism
2004/01/08 HPLC Separation of Catecholamines
2003/09/25 Hydrophobic and Hydrophilic Compound Separation
2003/09/24 Separation of Deoxyribo Nucleic Acid
Separation of Nucleic Bases
2003/09/19 Amino Sugars Analysis in Ion Exchange and Reverse Mode
2003/09/18 Dewetting Study in Aqueous Conditions
2003/09/11 Loading Study for Preparative Chromatography
Separation of Quaternary Amines
2003/08/12 Potassium Analysis in Organic Reaction Product
2003/08/06 Separation of Diacid: Ion Exclusion mode
2003/07/06 Effect of Acid on Separation of Xanthines
Separation of Glyphosate by Cation Exchange and Anion Exchange

SIELC Technologies Brochures

Obelisc®
LC Columns with Liquid Separation Cell Technology
1.01MB PDF (6 pages)
SHARC®
LC Column with Hydrogen Bonding Based Separation 
184 KB PDF (6 pages)
Primesep®
Columns, Methods, Applications
500KB PDF (30 pages)
Primesep®
Separation of Ions
New Alternative to Ion Chromatography
349KB PDF (18 pages)
Primesep®
Solving Problems of Pharmaceutical HPLC Analysis
490KB PDF (24 pages)
Promix®
Enter a New Era in Biomolecule Analysis with Promix Columns
Unsurpassed Selectivity and Peak Capacity for Peptides and Proteins
281KB PDF (8 pages)

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GML Series Nitrogen generator

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GIMITEC - gmLab Technologies

A nitrogen generator manufacturer, and trading service company.

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